On 9 January, VSPO! announced an affiliation with ex-Busokanojo member Kaminari Qpi as a solo member.
On 16 April, Yakumo Beni made her debut as a solo member.
On 9 June, VSPO! celebrated reaching 1 million total subscribers across all of its members.
On 14 September, VSPO! announced the addition of Aizawa Ema to the roster. She made her debut on 18 September as a solo member.
On 23 September, VSPO! announced the addition of Shinomiya Runa to the roster. She made her debut on 26 September as a solo member.
On 27 September, VSPO! released a statement in relation to Yakumo Beni's VALORANT smurfing controversy.
On 29 September, Riot Games's Japanese management team released a statement on VALORANT ' s Japanese official Twitter account, announcing that it was detected that several members of teams that are participating the VALORANT VICTORY CHALLENGE tournament scheduled for the following day, namely from VSPO!, Crazy Raccoon and ZETA DIVISION, were using smurf accounts to increase their co-players' rank using competitive mode, as well as being involved in a game with them; according to the statement, while these acts does not necessarily violate the Terms of Service of VALORANT, both of which are still considered highly discouraged acts, as it breaks the impartiality in competition.
VSPO!'s management team also revealed the details on the issue, in which Yakumo Beni had a contact with Rion (Crazy Raccoon), who confirmed that he would join Beni's game after her invitation on Twitter; and later joined by Zepher (also from Crazy Raccoon). After several matches, they were joined by another Crazy Raccoon member, Francisco, and CR Ojiji, the CEO of the team. It was later discovered that all members of Crazy Raccoon involved, minus CR Ojiji, were using smurf accounts.
Later on the same day, both VSPO! and Crazy Raccoon released their respective reports on their investigations regarding the issue, and both teams announced to take several measures:
Both Yakumo Beni and Zepher's activities would be suspended for a month.
It was discovered that Kaga Sumire was also invited by Rion to play VALORANT once, despite Sumire usually not playing the game, and Rion was using his smurf account in the match. Sumire's activities would be suspended for two weeks.
CR Ojiji would take a fifteen-percent cut in salary for a year, and delete all accounts for the game.
Rion was discovered to be letting his brother play on his account multiple times. His activities would be suspended for three months, and he would delete all accounts for the game.
Francisco was only given a warning from Crazy Raccoon, as he did not use smurf accounts habitually.
It was announced that Crazy Raccoon received a report from Amatsuki, an utaite (internet singer) and streamer who joined the team in July 2021, saying that he was also involved in a match that his co-players were using smurf accounts. Like Francisco, he was only given a warning from the team, as he had limited knowledge on eSports and was still inexperienced as a competitive player.
All involved talents' pre-existing and newly created accounts would be under inspections by the management team for VSPO! and a third-party inspection committee led by lawyers for Crazy Raccoon for a year.
Both teams apologized for inconveniences and disturbances caused by the controversy, and announced that they would strive to avoid further similar issues.
On 10 November, VSPO! announced their new official channel on Niconico.
On 16 November, VSPO! members' YouTube subscribers count reached 2 million in total.
On 27 November, VSPO! held their first project on Niconico, "Final Battle to Decide the Remote Bistro Queen" (リモートビストロクイーン決定戦). It was hosted by member Kisaragi Ren and Neo-Porte's Shirayuki Reid, with Tonakaito (a streamer) as the remote chef. All members participated in this project and were made into three groups.
On 17 December, VSPO! held their second project on Niconico, "Ideal Christmas Date Show" (理想のクリスマスデート品評会). It was hosted by indie VTuber Virtual Gorilla with Guilty (a streamer) as guest. Members who participated in this project were Tachibana Hinano, Hanabusa Lisa, and Kaminari Qpi.
On 24 December, VSPO! as a whole (except for the 2 new members) released a song cover of halyosy's Blessing in commemorative of VSPO! members' two millions youtube subscribers in total.
On 29 December, VSPO! had a collaboration event with GEO, "Who is the Number 1 Gamer in VSPO!" (ぶいすぽっ!令和3年最後の特別企画ゲームNo.1は誰だ!). It was hosted by casters Taiga Kishi and OooDa.
On 30 December, VSPO! held an event sponsored by Riot Games, a VALORANT match between VSPO Team vs Caster Team.