On 19 January, she and Reimu Endou held a sponsored Princess Connect stream as part of the game's 1st anniversary celebration.
On 10 February, Enna opened memberships on her YouTube channel.
On 19 February, Enna held a Higurashi fan concert on her channel, featuring songs from the Higurashi no Naku Koro ni anime. Original arrangements were done by Jairus Cambe and PrettyPatterns. Other EN Livers also featured as guest performers during the concert.
On 22 February, Enna reached 100,000 followers on Twitter.
On 27 February, Ethyria's debut celebration voice packs went up for sale.
On 15 March, Enna's White Day 2022 voice pack went up for sale.
On 4 April, Enna reached 200,000 subscribers on her YouTube channel.
On 22 April, Enna's Sakura Bloom 2022 voice pack went up for sale. This voice pack was only available in Japanese.
On 13 June, Enna reached 300,000 subscribers on her YouTube channel.
On 2 July, "Enna's Good Night & Good Morning Voice 2022" voice pack went up for sale. She was featured in the artwork for this series.
On 4 July, Enna's "Birds of time" single was made available for streaming via TuneCore. This was Enna's first single to be digitally distributed and sold through online retailers.
On 6 July, Enna reached over 300,000 followers on her Twitter account.
On 7 August, Enna's "LOVE SPACE" cover reached 1,000,000 views on YouTube, making it her first solo cover to reach this milestone.
On 17 August, Enna reached 400,000 YouTube subscribers on her YouTube channel and over 400,000 followers on her Twitter account.
On 13 October, Enna's "Halloween 2022" voice pack went up for sale.
On 21 November, Ethyria announced during a collab that they would be receiving new outfits 26-27 November (CST). Viewers could post predictions for Enna's outfit on Twitter using the hashtag #ENNATTIRE.
On 27 November, Enna revealed her second outfit, nicknamed "Queen of Spades." This outfit prominently features light pastel colors and her four-petaled flower motif. She wears lace-up boots, over-the-knee socks with garter straps, puffy sleeves with ruffles, a large bow with a purple spade crystal, and a light-blue waist cord in place of her shoulder bag. She also sports a short hairstyle with a braid and a laurel crown, and her diamond brooch is changed to a blue spade choker. Symbolizing her increased heavenly power, all of her wings have grown considerably larger, and she has a halo behind her head that can be toggled with her wings. She also has a translucent outer skirt and a blue-and-white bridal veil that can be toggled together. As part of Ethyria's queenly theme, Enna also wields an intricate silver staff with a sharp purple crystal, which she assures can be used as a spear if chat gets out of hand. During this stream, she also reached 500,000 subscribers on her YouTube channel. Later, new goods went up for sale to celebrate Ethyria's new outfits.