Nene is a cheerful, bubbly, and friendly girl who loves to talk and sing. She dreams of becoming an idol and having her own anime opening song. She's overconfident in games calling herself "Supernenechi," displaying good aiming skills in Apex despite being a beginner or having a 100% win rate in the first Among Us collaboration stream, however she can also be clumsy such as falling 16 times in her first Minecraft stream and failing Roboco-san's magma test. She often displays a cute smugness when she wins games, and pouts cutely whenever she loses. She playfully flirts with the other hololive members, with some examples including Lamy and Ina.
True to her idol dream, Nene has displayed her great singing ability during her karaoke streams and mini lives. She has mentioned that she knows how to dance (2-3 years experience), so fans can look forward to seeing her dance during her eventual 3d debut.
Polka and Lamy think that Nene is the toughest fifth gen member as she can easily bounce back to being optimistic, this can be seen in Nene's own recruitment to hololive as she applied to the agency four times, not losing hope until she was accepted in her fourth attempt.
Unlike Shirakami Fubuki, Nene is famously known for "husband-zoning" the audience, particularly non-Japanese viewers (dubbed by her fans as "Nene's husband collection,") as such, she refuses to "divorce" from her viewers or be called "friend."
Nene also flirts with other members of hololive using her "handsome" voice, calling members such as Lamy as "my Lamy" or sending kisses to girls. She admitted that she has many wives which include Lamy, Suisei, Ina and Kiara.
She likes playing casual games like LITTLE FRIENDS, PART TIME UFO, Good Job!, Rhythm Heaven Fever, and Minecraft. She also does singing practice streams, and sometimes does ASMR for her members-only streams.
Oftentimes, she streams during lunchtime to chat with her fans, and has a Super Chat thanking segment afterwards. Some fans ask Nene through Super Chat, "Will you be my waifu?", with Nene responding to them, "Yes! Welcome to Nene's husbands collection!" Female fans have also expressed interest, with Nene responding that wives are also welcome as part of her collection.
She sometimes says a few basic lines in English and Spanish when interacting with her audience, leading to an increased number of foreign fans on her livestreams; fans have dubbed her the nickname "Worldwide Nenechi" whenever this occurs. Nene also seems to get new nicknames every time she streams; with some examples including supernenechi, hypernenechi, ultranenechi, NENEMAX, and most importantly, Super Hyper Ultra Ultimate Deluxe Perfect Amazing Shining God 東方不敗 Master Ginga Victory Strong Cute Beautiful Galaxy Baby 無限 無敵 無双 NENECHI (!)
Nene used to add -aru at the end of her sentences. However, she stopped using it because she is not confident about it.
She greets he viewers with "Konnene"「こんねね」and says good bye with "Otsunene bye bye"「おつねね ばいばい」.